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PubMed , Arthritis Care & Research , vol

Proc Natl Acad Sci USA 1991;88:36336

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Summary and Quick Facts for Chronic Kidney Disease About 15% of adults in the United States, or 37 million people, suffer from chronic kidney disease (CKD)

Given its essential role in the detoxification of lipid hydroperoxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to specifically trigger ferroptosis and eradicate myeloid leukemia cells

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